Dr Mark's Suregrip Replacement Brush You replace your toothbrush regularly - what about your denture toothbrush? With daily use, you should replace the brush bristles on your SureGrip Denture Brush every 6 months. Simply peel the old brush off the ergo handle and replace with a new brush in just 60 seconds. A new brush head every 6 months will keep your SureGrip Brush - brushing perfectly. The SureGrip brush is self-cleaning and self-drying